#include <stdio.h>
#include <ctype.h>
#include <string.h>

#define ALPHABET_COUNT 26

const char* isPangram(const char* s) {
    int seen[ALPHABET_COUNT] = {0};
    int uniqueCount = 0;

    for (int i = 0; s[i] != '\0'; i++) {
        if (isalpha(s[i])) {
            int index = tolower(s[i]) - 'a';
            if (!seen[index]) {
                seen[index] = 1;
                uniqueCount++;
            }
        }
    }

    return (uniqueCount == ALPHABET_COUNT) ? "Yes" : "No";
}

int main() {
    char s[10001];
    fgets(s, sizeof(s), stdin);

    // Remove trailing newline if present
    size_t len = strlen(s);
    if (len > 0 && s[len - 1] == '\n') {
        s[len - 1] = '\0';
    }

    printf("%s\n", isPangram(s));
    return 0;
}