#include<stdio.h>
#include<string.h>
#include<ctype.h>

int main() {
    char str[1001];
    int alphabet[26] = {0};
    
    fgets(str, sizeof(str), stdin);
    
    for(int i=0;str[i] !='\0';i++)
    if(isalpha(str[i])) {
        char lower = tolower(str[i]);
        alphabet[lower - 'a'] =1;
    }
}

int isPangram =1;
for(int i=0;i<26;i++) {
if(alphabet[i] == 0) { 
    isPangram = 0;
    break;
}
}
if(isPangram)
printf("Yes\n");
else 
printf("No\n");
return 0;

}