// editor5
#include<iostream>
#include<string>
#include<cctype>
using namespace std;

bool ispangram(const string &s) {
    bool seen[26] = {false};
    for (char ch : s) {
        if (isalpha(ch)) {
            char lower = tolower(ch);
            int idx = lower - 'a';
            if (idx >= 0 && idx < 26) {
                seen[idx] = true;
            }
        }
    }
    for (int i = 0; i < 26; i++){
        if (!seen[i]) return false;
    }
    return true;
}
int main() {
    string s;
    getline(cin, s);
    if (isPangram(s)) {
        cout << "Yes";
    } else {
        cout << "No";
    }
    return 0;
    }