#include <stdio.h>
#include <string.h>
#include <ctype.h>
int main(){
    char str[10001];
    int alphabet[26] = {0};
    fgets(str, sizeof(str), stdin);
    for (int i = 0; str[i] != '\0'; i++) {
        if (isalpha(str[i])) {
            char lower = tolower(str[i]);
            alphapet[lower - 'a'] = 1;
        }
    }
       for (int i = 0; i < 26; i++) {
            if (alphabet== 0) {
            printf("No\n");
            return 0;
       }
   }
   printf("Yes\n");
   return 0;
}