// editor3
#include <iostream>
#ijnclude<string>
using namespace std;
int main() {
    string s;
    getline(cin, s);
    bool seen[16]= {false
;
         for (char c: s){
             if (c>= 'A' && c <= '2') {
                 c=c + 32;
             }
             if (c >= 'a' && c <='z') {
                 seen[c -'a'] =true;
             }
         }
         for(int i =0; i<26; i++){
             if (!seen[i]){
                 cout <<"No";
                 return 0;
             }
         }
         cout <<"Yes";
         return 0;
    }