#include <iostream>
#include <string>
#include <vector>
#include <cctype>
using namespace std;
int main(){
    string s;
    if(!getline(cin,s));
    return 0;
    vector<bool> alphabet(26,false);
    for (char c:s){
        if(isalpha(static_cast<unsigned char>(c)){
    int index=tolower(static_cast<unsigned char>(c)-'a';   
        alphabet[index]=true;
    }
}
bool ispangram=true;
for(int i=0;i<26;i++){
    if(!alphabet[i]){
        ispangram=false;
        break;
    }
}
if(ispangram){
    cout<<"Yes"<<endl;
}else{
    cout<<"No"<<endl;
    
}
}